You will most likely see the same issues in 2000 that you see in XP, as XP came from the NT/2000 branch of the tree. I personally was very pleased with ME. I ran it for 4 years before getting a new PC with XP on it, and I don't recall it ever crashing. I had been through 95, 95B, 98, NT4 and 98B before that, and never really felt like I had a stable system until ME. 2000 and XP seem just as stable, but may have 16bit issues.
YRMV